IPR&D and Goodwill - Summary of Carrying Value of IPR&D, Net of Impairment (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Indefinite-lived Intangible Assets [Roll Forward]
Beginning balance	$ 17,628	$ 17,628	$ 18,396
Change during the period	0	0	(768)
Ending balance	17,628	17,628	17,628
IPR&D
Indefinite-lived Intangible Assets [Roll Forward]
Acquired IPR&D, beginning balance	20,700	20,700	20,700
Acquired IPR&D, Change during the period	0	0	0
Acquired IPR&D, ending balance	20,700	20,700	20,700
Indefinite-lived Intangible Assets Accumulated Impairment [Roll Forward]
Beginning balance	(3,072)	(3,072)	(2,304)
Change during the period	0	0	(768)
Ending balance	$ (3,072)	$ (3,072)	$ (3,072)