Net Loss per Share - Summary of Calculation of Diluted Loss Per Share (Detail) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Numerator:
Net loss attributable to common shareholders basic	$ (211,843)	$ (180,552)	$ (145,437)
Adjustment for change in fair value of liability classified stock options	(28,534)	0	0
Net loss attributable to common shareholders diluted	$ (240,377)	$ (180,552)	$ (145,437)
Weighted-average common shares outstanding:
Basic (in shares)	51,553,869	50,382,497	38,022,014
Adjustment for dilutive effect of liability classified stock options	577,727	0	0
Diluted (in shares)	52,131,596	50,382,497	38,022,014
Net loss per common share – basic (in dollars per share)	$ (4.11)	$ (3.58)	$ (3.83)
Net loss per common share – diluted (in dollars per share)	$ (4.61)	$ (3.58)	$ (3.83)