Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Cash flows from operating activities:
Net loss	$ (31,136)	$ (13,641)
Items not involving cash:
Depreciation and amortization of property and equipment	775	496
Amortization of intangible assets	980	653
Stock-based compensation (recovery) expense	(2,716)	4,378
Amortization and impairment of operating lease right-of-use assets	1,062	329
Deferred income tax expense	351	0
Non-cash consideration from licensing agreement	(218)	0
Change in fair value of contingent consideration	0	22
Unrealized foreign exchange (gain) loss	(4,037)	451
Changes in non-cash operating working capital:
Accounts receivable	(6,467)	(345)
Prepaid expenses and other current assets	2,602	(7,660)
Accounts payable and accrued liabilities	1,065	(2,368)
Operating lease liabilities	252	(280)
Deferred revenue	0	(3,530)
Income taxes payable	0	193
Net cash used in operating activities	(37,487)	(21,302)
Cash flows from financing activities:
Proceeds from public offering, net of issuance costs (note 8a)	300,910	0
Issuance of common shares on exercise of options (note 8e)	1,447	362
Issuance of common shares through employee stock purchase plan	419	233
Deferred financing fees	60	(18)
Finance lease payments	(4)	(8)
Net cash provided by financing activities	302,832	569
Cash flows from investing activities:
Net (purchases) redemptions of short-term and long-term investments	(203,822)	22,036
Acquisition of property and equipment	(530)	(31)
Acquisition of intangible assets	(419)	0
Net cash (used in) provided by investing activities	(204,771)	22,005
Effect of exchange rate changes on cash and cash equivalents	460	(303)
Net change in cash and cash equivalents	61,034	969
Cash and cash equivalents, beginning of period	128,451	42,205
Cash and cash equivalents, end of period	189,485	43,174
Supplemental disclosure of non-cash investing and financing items:
Leased assets obtained in exchange for operating lease liabilities	1,982	8,012
Acquisition of property and equipment in accounts payable and accrued liabilities	$ 570	$ 242