Statements of Stockholders' Equity (Deficit) - USD ($)	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Deficit [Member]
Beginning Balance at Dec. 31, 2019	$ 4,380,545	$ 2,443	$ 90,108,492	$ (85,730,390)
Beginning Balance, Shares at Dec. 31, 2019		24,431,914
Stock-based compensation expense	1,628,558		1,628,558
Issuance of common stock from employee stock purchase plan	$ 119,416	$ 12	119,404
Issuance of common stock from employee stock purchase plan, shares	118,491	118,491
Issuance of common stock from warrant exercise		$ 38	(38)
Issuance of common stock from warrant exercise, shares	381,625	381,625
Issuance of common stock from stock option exercises	$ 215,816	$ 20	215,796
Issuance of common stock from stock option exercise, shares		199,111
Issuance of common stock from ATM offering, net of costs	3,595,713	$ 149	3,595,564
Issuance of common stock from ATM offering, net of costs, Shares		1,490,813
Net loss	(13,154,671)			(13,154,671)
Ending Balance at Dec. 31, 2020	$ (3,214,623)	$ 2,662	95,667,776	(98,885,061)
Ending Balance, Shares at Dec. 31, 2020	26,621,954	26,621,954
Stock-based compensation expense	$ 1,878,954		1,878,954
Issuance of common stock from employee stock purchase plan, shares	0
Issuance of common stock from warrant exercise, shares	0
Issuance of common stock, net of costs	$ 13,070,154	$ 575	13,069,579
Issuance of common stock, shares net		5,750,000
Issuance of common stock from stock option exercises	45,454	$ 7	45,447
Issuance of common stock from stock option exercise, shares		67,426
Issuance of common stock from ATM offering, net of costs	313,107	$ 22	313,085
Issuance of common stock from ATM offering, net of costs, Shares		217,100
Net loss	(8,537,952)			(8,537,952)
Ending Balance at Dec. 31, 2021	$ 3,555,094	$ 3,266	$ 110,974,841	$ (107,423,013)
Ending Balance, Shares at Dec. 31, 2021	32,656,480	32,656,480