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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate and Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Federal statutory rate 21.00% 21.00%
Change in valuation allowance 5.00% (3.00%)
Research and development credits   (1.00%)
Removal of net operating losses and other credits (25.00%) (11.00%)
Impact of state tax rate change   (2.00%)
Stock compensation and other permanent items (1.00%) (4.00%)