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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate and Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]    
Federal statutory rate 21.00% 21.00%
Change in valuation allowance (6.00%) (4.00%)
State income taxes, net of federal effect   7.00%
Research and development credits (1.00%) 3.00%
Removal of net operating losses and other credits (11.00%) (27.00%)
Impact of state tax rate change (2.00%) 4.00%
Stock compensation and other permanent items (1.00%) (4.00%)