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Stockholders' Equity - Summary of Estimated Fair Value of Stock Option Award (Detail) - Common stock options [Member]
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Stock-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Risk free interest rate   2.85%    
Expected option term   5 years 6 months    
Expected volatility of common stock   92.30%    
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Minimum [Member]        
Stock-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Risk free interest rate 1.80%   1.80% 2.66%
Expected option term 4 years 3 months 7 days   4 years 3 months 7 days 5 years 6 months
Expected volatility of common stock 101.46%   90.34% 90.15%
Maximum [Member]        
Stock-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Risk free interest rate 2.36%   2.55% 2.85%
Expected option term 5 years 9 months 7 days   6 years 6 years
Expected volatility of common stock 112.58%   112.58% 92.30%