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Summary of Significant Accounting Policies - Summary of Outstanding Potentially Dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share (Detail) - shares
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from the calculation of diluted net loss per share 5,760,761 4,948,909
Common stock subject to repurchase [Member]    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from the calculation of diluted net loss per share 18,791 45,000
Warrants to purchase common stock [Member]    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from the calculation of diluted net loss per share 2,713,561 2,744,500
Common stock options [Member]    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from the calculation of diluted net loss per share 3,017,624 2,131,624
Employee stock purchase plan [Member]    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from the calculation of diluted net loss per share 10,785 27,785