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Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2018
Accounting Policies [Abstract]  
Summary of Outstanding Potentially Dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share For the periods, the following table sets forth the outstanding potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to do so would be anti-dilutive:

 

 

Year Ended December 31,

 

 

 

2018

 

 

2017

 

Common stock subject to repurchase

 

 

18,791

 

 

 

45,000

 

Warrants to purchase common stock

 

 

2,713,561

 

 

 

2,744,500

 

Common stock options

 

 

3,017,624

 

 

 

2,131,624

 

Employee stock purchase plan

 

 

10,785

 

 

 

27,785

 

Total excluded securities

 

 

5,760,761

 

 

 

4,948,909

 

 

 

 

 

 

 

 

 

 

 

Summary of Calculation of Basic and Diluted Net Loss Per Share

The following table sets forth the calculation of basic and diluted net loss per share:

 

 

Year Ended December 31,

 

 

 

2018

 

 

2017

 

Net loss attributable to common shareholders for

   basic net loss per share

 

$

(7,566,080

)

 

$

(12,229,512

)

Adjustment for gain from change in fair value of dilutive
   warrants

 

 

 

 

(1,235,394

)

Net loss used for diluted net loss per share

 

$

(7,566,080

)

 

$

(13,464,906

)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Weighted-average shares used to compute basic net

   loss per share

 

 

16,602,422

 

 

 

14,897,885

 

Adjustment to reflect assumed exercise of warrants

 

 

 

 

53,151

 

Weighted-average shares used to compute diluted

   net loss per share

 

 

16,602,422

 

 

 

14,951,036

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net loss per share attributable to common shareholders:

 

 

 

 

 

 

 

 

   Basic

 

$

(0.46

)

 

$

(0.82

)

   Diluted

 

$

(0.46

)

 

$

(0.90

)