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Stockholders' Equity - Summary of Estimated Fair Value of Stock Option Award (Detail) - Common stock options [Member]
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Stock-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Risk free interest rate 2.85% 1.93%    
Risk free interest rate, minimum     2.66% 1.93%
Risk free interest rate, maximum     2.85% 2.16%
Expected option term 5 years 6 months 5 years 6 months    
Expected volatility of common stock 92.30% 98.23%    
Expected volatility of common stock, minimum     90.15% 94.05%
Expected volatility of common stock, maximum     92.30% 98.23%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Minimum [Member]        
Stock-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected option term     5 years 6 months 5 years 6 months
Maximum [Member]        
Stock-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected option term     6 years 6 years