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Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2018
Accounting Policies [Abstract]  
Summary of Outstanding Potentially Dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share

For the periods presented, the following table sets forth the outstanding potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because their inclusion would be anti-dilutive:

 

 

 

Three Months Ended

June 30,

 

 

Six Months Ended

June 30,

 

 

 

2018

 

 

2017

 

 

2018

 

 

2017

 

Common stock subject to repurchase

 

 

30,165

 

 

 

45,000

 

 

 

37,582

 

 

 

45,000

 

Warrants to purchase common stock

 

 

2,797,561

 

 

 

2,719,932

 

 

 

2,797,561

 

 

 

2,758,746

 

Common stock options

 

 

3,017,624

 

 

 

2,131,624

 

 

 

3,017,624

 

 

 

2,131,624

 

Employee stock purchase plan

 

 

19,144

 

 

 

11,785

 

 

 

26,047

 

 

 

16,970

 

Total excluded securities

 

 

5,864,494

 

 

 

4,908,341

 

 

 

5,878,814

 

 

 

4,952,340

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Summary of Calculation of Basic and Diluted Net Loss Per Share

The following table sets forth the calculation of basic and diluted net loss per share:

 

 

Three Months Ended

 

 

Six Months Ended

 

 

June 30,

 

 

June 30,

 

 

2018

 

 

2017

 

 

2018

 

 

2017

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net loss attributable to common shareholders for

   basic net loss per share

$

(2,303,193

)

 

$

(1,625,969

)

 

$

(4,285,980

)

 

$

(6,678,008

)

Adjustment for loss from change in fair value of warrants

 

-

 

 

 

(429,702

)

 

 

-

 

 

 

(429,702

)

Net loss used for diluted net loss per share

$

(2,303,193

)

 

$

(2,055,671

)

 

$

(4,285,980

)

 

$

(7,107,710

)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Weighted-average shares used to compute basic net loss

   per share

 

16,425,468

 

 

 

15,343,325

 

 

 

15,926,253

 

 

 

14,435,818

 

Adjustment to reflect assumed exercise of warrants

 

-

 

 

 

77,629

 

 

 

-

 

 

 

38,815

 

Weighted-average shares used to compute diluted net loss

   per share

 

16,425,468

 

 

 

15,420,954

 

 

 

15,926,253

 

 

 

14,474,633

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net loss per share attributable to common shareholders:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

   Basic

$

(0.14

)

 

$

(0.11

)

 

$

(0.27

)

 

$

(0.46

)

   Diluted

$

(0.14

)

 

$

(0.13

)

 

$

(0.27

)

 

$

(0.49

)