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Stockholders' Equity - Summary of Estimated Fair Value of Stock Option Award (Detail) - Common stock options [Member]
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Stock-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Risk free interest rate 2.66% 2.16%
Expected option term 6 years 6 years
Expected volatility of common stock 90.15% 94.05%
Expected dividend yield 0.00% 0.00%