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Debt - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended
Aug. 04, 2016
Jul. 31, 2016
May 31, 2014
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Debt Instrument [Line Items]            
Repayment of principal and accrued interest       $ 4,500,000    
Warrant exercise price per share       $ 3.29 $ 16.73  
Loan and security agreement [Member]            
Debt Instrument [Line Items]            
Loan and security agreement, interest incurred       $ 148,500 $ 250,938  
Square 1 Bank [Member] | Loan and security agreement [Member]            
Debt Instrument [Line Items]            
Loan and security agreement, available credit     $ 4,500,000      
Loan and security agreement, amount drawn           $ 4,500,000
Fixed interest rate           5.50%
Repayment of principal and accrued interest $ 4,500,000          
Line of credit facility, loan origination cost     $ 82,685      
Debt instrument, unamortized discount 38,000          
Warrants exercisable, stock issued           22,881
Warrant exercise price per share           $ 5.90
Square 1 Bank [Member] | Loan and security agreement [Member] | Warrants to purchase common stock [Member]            
Debt Instrument [Line Items]            
Debt instrument, unamortized discount $ 59,000          
Common stock shares issued upon conversion of warrants   9,887        
Warrant value recorded in equity           $ 108,122