Exhibit 8.1

LIST OF SUBSIDIARIES

• WuXi AppTec Holding Company, Inc., incorporated in the United States of America.

• WX (BVI) Limited, incorporated in the British Virgin Islands.

• WuXi AppTec (BVI) Inc., incorporated in the British Virgin Islands.

• WuXi AppTec, Inc., incorporated in the United States of America.

• Shanghai AppTec(HK) Limited, incorporated in HongKong.

• Kaipara Enterprises Limited, incorporated in Cyprus.

• Klivia Investments Sp. zo.o., incorporated in Poland.

• Klivia Investments Sp. zo.o. Luxembourg Branch, incorporated in Luxembourg.

• WuXi AppTec Co., Ltd., incorporated in the People’s Republic of China.

• WuXi AppTec (Shanghai) Co., Ltd., incorporated in the People’s Republic of China.

• WuXi AppTec (Suzhou) Co., Ltd., incorporated in the People’s Republic of China.

• Shanghai SynTheAll PharmaTech Co., Ltd., incorporated in the People’s Republic of China.

• WuXiAppTec (Tianjin) Co., Ltd., incorporated in the People’s Republic of China.

• WuXi AppTec Biotechnology Co., Ltd., incorporated in the People’s Republic of China.

• WuXi AppTec (Wuhan) Co., Ltd., incorporated in the People’s Republic of China.

• Shanghai SynTheAll PharmaTech Co., Ltd. Changzhou Branch, incorporated in the People’s Republic of China.