X0306 4 2016-12-16 0001358762 REATA PHARMACEUTICALS INC RETA 0001402856 McGaughy R Kent Jr C/O CPMG, INC. 2000 MCKINNEY AVE, STE 2125 DALLAS TX 75201 true true Class A common stock 2016-12-16 4 P 0 164753 22.9909 A 1916642 I See footnote Class A common stock 4591 I By Lagos Trust Class A common stock 280 I By Traweek Children's Trust Class A common stock 2739 I See footnote Class A common stock 25004 D This price reflects the weighted average purchase price for open-market purchases on December 16, 2016, within a $1.00 range. The actual prices for these transactions range from $22.885 to $23.00, inclusive. The Reporting Person undertakes to provide upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of Shares purchased at each separate price within the ranges set forth in footnote (1) to this Form 4. The Reporting Person is trustee of Lagos Trust. The Reporting Person is trustee of Traweek Children's Trust. These shares of Class A common stock are held in escrow for a charitable donee by American Stock Transfer &Trust Company, LLC. These shares of Class A common stock are held in various funds for which CPMG, Inc. serves as investment manager. The Reporting Person is a co-director and co-shareholder of CPMG, Inc. The Reporting Person disclaims beneficial ownership of the shares except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of the shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. /s/ R. Kent McGaughy, Jr. 2016-12-20