X0306 4 2015-11-30 0 0001401914 Cerulean Pharma Inc. CERU 0001205236 WALT DAVID R C/O CERULEAN PHARMA INC. 840 MEMORIAL DRIVE CAMBRIDGE MA 02139 1 0 0 0 Common Stock 2015-11-30 4 P 0 5374 3.249 A 17491 D Represents the weighted average purchase price for shares purchased in multiple transactions. Purchase prices ranged from $3.19 to $3.29 per share. Upon request of the staff of the Securities and Exchange Commission, the issuer or a security holder of the issuer, the reporting person will provide full information regarding the number of shares purchased at each separate price. /s/ Alejandra Carvajal, as attorney-in-fact for David R. Walt 2015-12-02