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Property and Equipment
12 Months Ended
Dec. 31, 2022
Property, Plant and Equipment [Abstract]  
Property and Equipment Property and Equipment    
Property and equipment consisted of the following at December 31 (in thousands):
Useful Life
(Years)
20222021
Manufacturing equipment5$22,094 $19,067 
Prototype instruments210,421 2,128 
Capitalized software and computer equipment318,670 5,597 
Furniture and fixtures52,153 1,927 
Leasehold improvementsVarious20,297 19,641 
Construction in progress7,055 7,143 
Total property and equipment, gross80,690 55,503 
Less: Accumulated depreciation and amortization(36,233)(28,460)
Total property and equipment, net$44,457 $27,043 
Prototype instruments consist of various CosMx SMI , GeoMx DSP, and nCounter instruments used in internal testing and other development activities. Depreciation and amortization expense related to property and equipment for the years ended December 31, 2022, 2021 and 2020 totaled approximately $8.1 million, $5.9 million and $5.7 million, respectively.