Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenue:
Revenue	$ 31,080	$ 31,617
Costs and expenses:
Cost of product revenue	14,778	15,623
Research and development	17,417	15,063
Selling, general and administrative	36,355	26,799
Total costs and expenses	68,550	57,485
Loss from operations	(37,470)	(25,868)
Other income (expense):
Interest income	151	118
Interest expense	(1,883)	(1,870)
Other income (expense), net	(217)	(32)
Total other expense, net	(1,949)	(1,784)
Net loss before provision for income tax	(39,419)	(27,652)
Provision for income tax	(81)	(60)
Net loss	$ (39,500)	$ (27,712)
Net loss per share - basic (in dollars per share)	$ (0.86)	$ (0.62)
Net loss per share - diluted (in dollars per share)	$ (0.86)	$ (0.62)
Weighted average shares used in computing basic net loss per share (in shares)	45,998	44,669
Weighted average shares used in computing diluted net loss per share (in shares)	45,998	44,669
Total product and service revenue
Revenue:
Revenue	$ 30,841	$ 31,394
Product
Revenue:
Revenue	26,571	27,708
Costs and expenses:
Cost of product revenue	11,472	12,046
Service revenue
Revenue:
Revenue	4,270	3,686
Costs and expenses:
Cost of product revenue	3,306	3,577
Collaboration revenue
Revenue:
Revenue	$ 239	$ 223