Collaboration Agreements - Additional Information (Detail) $ in Thousands	1 Months Ended		12 Months Ended
	Jan. 31, 2020 shares	Aug. 31, 2017 USD ($) employee	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration			$ 145,085	$ 117,316	$ 125,568
Celgene Corporation | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Proceeds from Collaborators					1,100
Collaboration					4,400
Lam Research Corporation | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Proceeds from Collaborators					14,900
Collaboration			$ 0	$ 4,800	$ 16,300
Maximum Amount Of Royalties Payable, Ratio To License And Service Revenue		3
Reimbursement Of Counterparty Costs, Maximum Number Of Employees | employee		10
Class Of Warrant Or Right, Number Of Warrants Or Rights Exercised | shares	1,000,000
Lam Research Corporation | Collaborative Arrangement | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration		$ 50,000
Class of Warrant or Right, Outstanding | shares	407,247