Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Revenue:
Revenue	$ 37,150	$ 31,845	$ 102,630	$ 81,054
Costs and expenses:
Cost of product and service revenue	17,154	13,962	48,258	35,691
Research and development	19,117	14,993	51,342	48,234
Selling, general and administrative	30,253	20,474	83,907	66,107
Total costs and expenses	66,524	49,429	183,507	150,032
Loss from operations	(29,374)	(17,584)	(80,877)	(68,978)
Other income (expense):
Interest income	153	333	502	1,516
Interest expense	(1,876)	(4,154)	(5,614)	(11,153)
Other income (expense), net	(223)	159	79	(1,116)
Loss on extinguishment of debt and termination of revolving loan facility	0	0	0	(7,143)
Total other expense, net	(1,946)	(3,662)	(5,033)	(17,896)
Net loss before provision for income tax	(31,320)	(21,246)	(85,910)	(86,874)
Provision for income tax	59	(71)	(83)	(200)
Net loss	$ (31,261)	$ (21,317)	$ (85,993)	$ (87,074)
Net loss per share - basic and diluted (in dollars per share)	$ (0.69)	$ (0.56)	$ (1.90)	$ (2.31)
Weighted average shares used in computing basic and diluted net loss per share (in shares)	45,558	38,081	45,170	37,624
Total product and service revenue
Revenue:
Revenue	$ 36,924	$ 30,090	$ 101,950	$ 75,730
Collaboration revenue
Revenue:
Revenue	$ 226	$ 1,755	$ 680	$ 5,324