Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020
Revenue:
Revenue	$ 33,863	$ 22,604	$ 65,480	$ 49,209
Costs and expenses:
Cost of product and service revenue	15,481	10,712	31,104	21,729
Research and development	17,162	15,739	32,225	33,241
Selling, general and administrative	26,855	19,912	53,654	45,633
Total costs and expenses	59,498	46,363	116,983	100,603
Loss from operations	(25,635)	(23,759)	(51,503)	(51,394)
Other income (expense):
Interest income	231	479	349	1,183
Interest expense	(1,868)	(4,116)	(3,738)	(6,999)
Other income (expense), net	334	332	302	(1,275)
Loss on extinguishment of debt and termination of revolving loan facility	0	0	0	(7,143)
Total other expense, net	(1,303)	(3,305)	(3,087)	(14,234)
Net loss before provision for income tax	(26,938)	(27,064)	(54,590)	(65,628)
Provision for income tax	(82)	(69)	(142)	(129)
Net loss	$ (27,020)	$ (27,133)	$ (54,732)	$ (65,757)
Net loss per share - basic and diluted (in dollars per share)	$ (0.60)	$ (0.72)	$ (1.22)	$ (1.76)
Weighted average shares used in computing basic and diluted net loss per share (in shares)	45,274	37,785	44,973	37,392
Total product and service revenue
Revenue:
Revenue	$ 33,632	$ 21,144	$ 65,026	$ 45,640
Collaboration revenue
Revenue:
Revenue	$ 231	$ 1,460	$ 454	$ 3,569