Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Revenue:
Revenue	$ 31,617	$ 26,605
Costs and expenses:
Cost of product and service revenue	15,623	11,017
Research and development	15,063	17,502
Selling, general and administrative	26,799	25,721
Total costs and expenses	57,485	54,240
Loss from operations	(25,868)	(27,635)
Other income (expense):
Interest income	118	704
Interest expense	(1,870)	(2,883)
Other expense, net	(32)	(1,607)
Loss on extinguishment of debt and termination of revolving loan facility	0	(7,143)
Total other expense, net	(1,784)	(10,929)
Net loss before provision for income tax	(27,652)	(38,564)
Provision for income tax	(60)	(60)
Net loss	$ (27,712)	$ (38,624)
Net loss per share - basic and diluted (in dollars per share)	$ (0.62)	$ (1.04)
Weighted average shares used in computing basic and diluted net loss per share (in shares)	44,669	36,999
Total product and service revenue
Revenue:
Revenue	$ 31,394	$ 24,496
Collaboration revenue
Revenue:
Revenue	$ 223	$ 2,109