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Net Loss Per Share - Summary of Outstanding Options, Warrants and preferred stock were Excluded from Computation of Diluted Net Loss Per Share (Detail) - shares
shares in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Options to purchase common stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Anti-dilutive securities excluded from computation of earnings per share 4,069 3,295 2,113
Common Stock [Member] | Warrants [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Anti-dilutive securities excluded from computation of earnings per share 572 572 618