Amount due from customers or clients, within one year of the balance sheet date (or the normal operating cycle, whichever is longer), for goods or services (including trade receivables) that have been delivered or sold in the normal course of business, reduced to the estimated net realizable fair value by an allowance established by the entity of the amount it deems uncertain of collection.

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Collaboration Agreement - Additional Information (Detail) (USD $)	1 Months Ended	3 Months Ended		1 Months Ended
	Oct. 31, 2014	Mar. 31, 2015	Mar. 31, 2014	Mar. 31, 2014	Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Maximum success-based milestone payments	$ 55,000,000
Amount of certain milestones achieved in account receivable		10,465,000us-gaap_AccountsReceivableNetCurrent			12,436,000us-gaap_AccountsReceivableNetCurrent
Revenue recognized under collaboration agreement		761,000us-gaap_RecognitionOfDeferredRevenue	0us-gaap_RecognitionOfDeferredRevenue
Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Amount of certain milestones achieved in account receivable					6,000,000
Revenue recognized under collaboration agreement		700,000	0
Deferred revenue recorded under collaboration agreement		8,100,000
Upfront Payment Arrangement [Member] \| Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Collaboration agreement upfront payment				5,800,000
Scenario, Forecast [Member] \| Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recognized under collaboration agreement		2,000,000
Maximum [Member] \| Scenario, Forecast [Member] \| Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Maximum success-based milestone payments		$ 17,000,000