Amount due from customers or clients, within one year of the balance sheet date (or the normal operating cycle, whichever is longer), for goods or services (including trade receivables) that have been delivered or sold in the normal course of business, reduced to the estimated net realizable fair value by an allowance established by the entity of the amount it deems uncertain of collection.

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Collaboration Agreement - Additional Information (Detail) (USD $)	1 Months Ended	12 Months Ended			1 Months Ended
	Oct. 31, 2014	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012	Mar. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Maximum success-based milestone payments	$ 40,000,000
Amount of certain milestones achieved in account receivable		12,436,000us-gaap_AccountsReceivableNetCurrent	8,331,000us-gaap_AccountsReceivableNetCurrent
Revenue recognized under collaboration agreement		3,096,000us-gaap_RecognitionOfDeferredRevenue	0us-gaap_RecognitionOfDeferredRevenue	0us-gaap_RecognitionOfDeferredRevenue
Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Maximum success-based milestone payments		11,800,000
Amount of certain milestones achieved in account receivable		6,000,000
Revenue recognized under collaboration agreement		2,900,000	0	0
Deferred revenue recorded under collaboration agreement		8,900,000
Upfront Payment Arrangement [Member] \| Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Collaboration agreement upfront payment					5,800,000
Scenario, Forecast [Member] \| Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recognized under collaboration agreement		2,600,000
Maximum [Member] \| Scenario, Forecast [Member] \| Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Maximum success-based milestone payments		$ 17,000,000