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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
9 Months Ended 12 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Operating activities:          
Net loss $ (20,454) $ (11,847) $ (17,708) $ (10,932) $ (12,768)
Adjustments to reconcile net loss to net cash used in operating activities          
Depreciation and amortization 1,360 1,467 1,947 1,454 972
Amortization of debt discount 162 113 136 330  
Stock-based compensation 766 566 745 243 144
Revaluation of preferred stock warrant liability (1,156) (150) 387 (73) (15)
Net amortization of premium on short term investments 89        
Interest accrued on convertible promissory notes       87  
Interest accrued on long-term note loan 182 63 90    
Loss on disposal of property and equipment 1 1 3   117
Changes in operating assets and liabilities          
Accounts receivable (3,470) (999) (210) (965) 62
Inventory (336) (409) (1,884) (1,338) (233)
Prepaid expenses and other (1,500) (1,443) 221 (1,100) (139)
Related party loans and other assets (275) (7) 118 (58) (128)
Accounts payable 1,121 628 103 (1,231) 1,008
Accrued liabilities 2,038 1,379 1,830 781 454
Deferred revenue 556 31 146 624 49
Deferred rent (567) (533) (732) 1,486 (488)
Net cash used in operating activities (21,483) (11,140) (14,808) (10,692) (10,965)
Investing activities:          
Purchases of property and equipment (500) (312) (428) (2,688) (1,932)
Purchase of short-term investments (33,006)        
Increase in restricted cash       (112)  
Net cash used in investing activities (33,506) (312) (428) (2,800) (1,932)
Financing activities:          
Proceeds from issuance of preferred stock and warrants     15,132 14,883 14,985
Proceeds from initial public offering 47,374        
Proceeds from issuance of convertible promissory notes and warrants       5,000  
Proceeds from issuance of long-term debt 5,000 7,500 13,000 5,004 1,197
Repayment of long-term debt (163) (1,654) (1,706) (4,899) (681)
Deferred offering costs     (553)    
Proceeds from exercise of stock options 378 99 183 6 23
Proceeds from exercise of common stock warrant     4    
Net cash provided by (used in) financing activities 52,589 5,945 26,060 19,994 15,524
Net increase (decrease) in cash and cash equivalents (2,400) (5,507) 10,824 6,502 2,627
Cash and cash equivalents:          
Beginning of period 21,692 10,868 10,868 4,366 1,739
End of period 19,292 5,361 21,692 10,868 4,366
Supplemental disclosures:          
Accretion of preferred stock 4,653 5,515 7,533 5,251 4,351
Accrual of offering costs     1,212    
Cash paid for interest 1,072 331 563 167 94
Issuance of preferred stock warrants with debt 137 263 648 661  
Issuance of preferred stock warrants with equity       1,867  
Conversion of convertible promissory notes and accrued interest into Series D preferred stock       5,087  
Conversion of convertible preferred stock to common stock 108,275        
Conversion of convertible preferred stock warrants to common stock warrants 2,514        
Non cash capital lease $ 410