144 0001625110 XXXXXXXX LIVE 0001401667 PUMA BIOTECHNOLOGY, INC. 001-35703 10880 WILSHIRE BLVD. SUITE 2150 LOS ANGELES CA 90024 (424) 248-6500 Dorval Allison Director Common Stock Muriel Siebert & Co., Inc.

4141 NE 2nd Avenue, Suite 201 Miami FL 33137

11000 39545.00 48238850 06/13/2024 NASDAQGS Common Stock 06/13/2024 Restricted Stock Unit Vesting PUMA BIOTECHNOLOGY, INC. N 27000 06/13/2024 Compensation for Services Rendered Y 06/13/2024 03/06/2024 /s/ Chris Culotta, Attorney-in-Fact for Allison Dorval