Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019
Operating activities:
Net loss	$ (13,538)	$ (47,511)
Adjustments to reconcile net loss to net cash provided by operating activities:
Depreciation and amortization	4,153	4,235
Stock-based compensation	19,537	33,578
Disposal of property and equipment		54
Loss on debt extinguishment		8,047
Changes in operating assets and liabilities:
Accounts receivable, net	4,909	(4,573)
Inventory, net	279	(635)
Prepaid expenses and other	(119)	2,258
Other current assets	(3,103)	1,457
Accounts payable	(7,416)	(5,613)
Accrued expenses	155	27,820
Deferred rent	(44)
Post-marketing commitment liability	(125)	9,000
Net cash provided by operating activities	4,688	28,117
Investing activities:
Purchase of property and equipment	(12)
Purchase of available-for-sale securities	(16,376)	(127,974)
Sale of available-for-sale securities		28,135
Maturity of available-for-sale securities	51,546	66,462
Purchase of intangible assets	(10,000)
Net cash provided by (used in) investing activities	25,158	(33,377)
Financing activities:
Net proceeds from shares issued under employee stock plans	2	1,276
Proceeds from debt	8,444	25,000
Payment of debt	(8,444)	(80,000)
Payment of debt extinguishment costs		(7,793)
Payment of debt issuance costs		(5,625)
Net cash provided by (used in) financing activities	2	(67,142)
Net increase (decrease) in cash, cash equivalents and restricted cash	29,848	(72,402)
Cash, cash equivalents and restricted cash, beginning of period	73,210	112,738
Cash, cash equivalents and restricted cash, end of period	103,058	40,336
Supplemental disclosures of non-cash investing and financing activities:
Intangibles in accrued expenses	30,000
Supplemental disclosure of cash flow information:
Interest paid	$ 4,721	$ 7,914