Note 2 - Significant Accounting Policies (Details Textual) $ in Thousands	1 Months Ended	12 Months Ended
	Sep. 30, 2022 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Sublease Agreement, Potential Milestone Payments		$ 579,800
Restricted Cash		2,100	$ 2,600
Cash and Cash Equivalents, and Restricted Cash In Excess of Insured Limits		84,400
Accounts Receivable, Credit Loss Expense (Reversal)		881	0	$ (1,000)
Accounts Receivable, after Allowance for Credit Loss		$ 47,837	40,350
Average Incremental Borrowing Rate		10.90%
Acquired In-process Research and Development		$ 0	7,000	0
Potential Milestone Payments		102,500
Amortization of Intangible Assets		9,700	8,000	$ 8,000
Finite-Lived Intangible Asset, Expected Amortization, Year One		9,739
Finite-Lived Intangible Asset, Expected Amortization, Year Seven		2,400
Payroll Tax Credit			3,800
Finite-Lived Intangible Asset, Expected Amortization, Year Two		9,739
Finite-Lived Intangible Asset, Expected Amortization, Year Three		9,739
Finite-Lived Intangible Asset, Expected Amortization, Year Four		9,739
Finite-Lived Intangible Asset, Expected Amortization, Year Five		9,739
Finite-Lived Intangible Asset, Expected Amortization, Year Six		9,700
Pfizer License Agreement [Member]
Potential Milestone Payments			12,500
NERLYNX [Member]
Revenue from Contract with Customer, Including Assessed Tax			250,000
Takeda License Agreement [Member]
Acquired In-process Research and Development	$ 7,000
Selling, General and Administrative Expenses [Member]
Operating Lease, Impairment Loss		$ 600
Computer Equipment [Member]
Property, Plant and Equipment, Useful Life (Year)		3 years
Telephone Equipment [Member]
Property, Plant and Equipment, Useful Life (Year)		3 years
Furniture and Fixtures [Member]
Property, Plant and Equipment, Useful Life (Year)		7 years
Vendor Related Damaged Inventory [Member]
Reimbursement Receivable		$ 700
CARES Act [Member]
Reimbursement Receivable			1,900
Customer Concentration Risk [Member] | Customers With More than 10% Accounts Receivable [Member]
Accounts Receivable, after Allowance for Credit Loss		$ 32,300	$ 28,900
Customer Concentration Risk [Member] | Revenue Benchmark [Member]
Number of Major Customers		4	2	2
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | Customer 1 [Member]
Concentration Risk, Percentage		31.40%	35.00%	31.00%
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | Customer 2 [Member]
Concentration Risk, Percentage		17.20%	20.00%	22.00%
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | Customer 3 [Member]
Concentration Risk, Percentage		15.20%
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | Customer 4 [Member]
Concentration Risk, Percentage		11.90%