Condensed Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Total revenue	$ 228,031,000	$ 253,155,000	$ 225,110,000
Operating costs and expenses:
Cost of sales	55,093,000	63,701,000	39,374,000
Selling, general and administrative	89,978,000	116,294,000	118,488,000
Research and development	52,240,000	71,870,000	97,650,000
Acquired in-process research and development	7,000,000	0	0
Total operating costs and expenses	204,311,000	251,865,000	255,512,000
Income (loss) from operations	23,720,000	1,290,000	(30,402,000)
Other income (expenses):
Interest income	813,000	160,000	489,000
Interest expense	(11,592,000)	(12,807,000)	(14,046,000)
Legal verdict expense	(12,456,000)	(9,591,000)	(16,196,000)
Loss on debt extinguishment	0	(8,146,000)	0
Other income (expense)	(28,000)	292,000	367,000
Total other expenses	(23,263,000)	(30,092,000)	(29,386,000)
Net income (loss) before income taxes	457,000	(28,802,000)	(59,788,000)
Income tax expense	(455,000)	(324,000)	(207,000)
Net income (loss)	$ 2,000	$ (29,126,000)	$ (59,995,000)
Net income (loss) per share of common stock—basic (in dollars per share)	$ 0	$ (0.72)	$ (1.52)
Net income (loss) per share of common stock—diluted (in dollars per share)	$ 0	$ (0.72)	$ (1.52)
Weighted-average shares of common stock outstanding—basic (in shares)	44,674,501	40,638,852	39,576,107
Weighted-average shares of common stock outstanding—diluted (in shares)	44,929,998	40,638,852	39,576,107
Product [Member]
Revenues:
Total revenue	$ 200,023,000	$ 189,064,000	$ 196,728,000
License [Member]
Revenues:
Total revenue	0	51,750,000	22,700,000
Royalty [Member]
Revenues:
Total revenue	$ 28,008,000	$ 12,341,000	$ 5,682,000