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Note 9 - Accrued Expenses (Details Textual) - USD ($)
$ in Thousands
1 Months Ended
Nov. 02, 2021
Oct. 29, 2021
Jan. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Accrued Legal Verdict Expense, Noncurrent       $ 0 $ 24,822
Restructuring, Percentage of Reduction in Headcount 13.00%        
Employee Severance [Member]          
Restructuring and Related Cost, Cost Incurred to Date $ 1,200     100  
Hsu v. Puma Biotechnology, Inc., [Member]          
Litigation Settlement, Amount Awarded to Other Party $ 54,200 $ 54,200      
Accrued Legal Verdict Expense, Noncurrent       $ 2,900  
Hsu v. Puma Biotechnology, Inc., [Member] | Subsequent Event [Member]          
Litigation Settlement, Amount Awarded to Other Party     $ 54,200    
Payments for Legal Settlements     $ 27,200