Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 63,131	$ 85,293
Marketable securities	18,975	8,096
Accounts receivable, net of allowance for credit loss of $0 and $1,000	32,526	25,543
Inventory, net	7,109	3,454
Prepaid expenses, current	8,984	11,262
Restricted cash, current	8,850	8,850
Other current assets	447	3,641
Total current assets	140,022	146,139
Lease right-of-use assets, net	14,017	16,404
Property and equipment, net	1,756	2,481
Intangible assets, net	66,125	74,140
Restricted cash, long-term	3,311	3,311
Prepaid expenses and other, long-term	1,354	1,745
Total assets	226,585	244,220
Current liabilities:
Accounts payable	11,174	12,076
Accrued expenses, current	92,575	61,325
Accrued in-licensed rights, current	0	20,993
Post-marketing commitment liability, current	2,263	2,481
Lease liabilities, current	3,574	3,094
Current portion of long-term debt	0	14,286
Total current liabilities	109,586	114,255
Accrued expenses, long-term	915	25,963
Lease liabilities, long-term	15,975	19,549
Post-marketing commitment liability, long-term	5,463	6,379
Total long-term debt, net	97,092	84,025
Total liabilities	229,031	250,171
Commitments and contingencies (Note 14)
Stockholders' deficit:
Common stock - $.0001 par value per share; 100,000,000 shares authorized; 41,175,507 shares issued and outstanding at December 31, 2021 and 40,086,387 issued and outstanding at December 31, 2020	4	4
Additional paid-in capital	1,364,309	1,331,676
Accumulated other comprehensive income	(2)	0
Accumulated deficit	(1,366,757)	(1,337,631)
Total stockholders' deficit	(2,446)	(5,951)
Total liabilities and stockholders' deficit	$ 226,585	$ 244,220