X0306 4 2021-08-16 0 0001401040 DiaMedica Therapeutics Inc. DMAC 0001760016 Pilnik Richard D. TWO CARLSON PARKWAY, SUITE 260 MINNEAPOLIS MN 55447 1 0 0 0 Voting Common Shares, no par value per share 2021-08-16 4 P 0 2500 3.2126 A 83065 D Voting Common Shares, no par value per share 2021-08-16 4 P 0 12500 3.2826 A 95565 D Includes 7,588 voting common shares issuable upon settlement of deferred share units granted under the DiaMedica Therapeutics Inc. Deferred Share Unit Plan and 19,887 shares issuable upon settlement of deferred stock units granted under the DiaMedica Therapeutics Inc. 2019 Omnibus Incentive Plan. /s/ Amy Culbert, attorney-in-fact 2021-08-17