144 0001400240 XXXXXXXX LIVE 0001682852 Moderna, Inc. 001-38753 325 BINNEY STREET CAMBRIDGE MA 02142 6177146500 Flagship Pioneering Inc. Affiliate Common Fidelity Brokerage Services LLC

900 Salem Street Smithfield RI 02917

23853 703305.71 390679512 12/11/2025 NASDAQ Common 12/11/2025 Options Granted - 08/10/2016 Issuer N 23853 12/11/2025 Cash Y The securities reported in this Form 144 were sold by Flagship Pioneering, Inc. in connection with the cashless exercise of options to purchase shares of the Issuers Common Stock, which options were set to expire on February 23, 2026. 12/11/2025 /s/ Joshua Schmitt, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Flagship Pioneering, Inc.