DEPRECIATION, SHARE-BASED PAYMENTS, EMPLOYEE AND OTHER EXPENSES (Tables)

12 Months Ended

Dec. 31, 2020

DEPRECIATION, SHARE-BASED PAYMENTS, EMPLOYEE AND OTHER EXPENSES

Schedule of depreciation, share-based payments, employee and other expenses

	For the years ended December 31,
	2020		2019		2018
EXPENSES
Selling expenses
Share-based payment	$	320,886	$	188,930	$	170,416
Cash-based employee expenses		891,784		526,769		352,837
Other expenses		984,133		930,286		829,912
	$	2,196,803	$	1,645,985	$	1,353,165
General and administrative expenses
Depreciation		280,949		182,202		60,206
Share-based payments		2,820,369		1,748,660		2,147,832
Cash-based employee expenses		3,149,313		2,725,814		2,498,005
Litigation expenses		284,729		81,171		540,125
Employee termination expenses		—		26,050		761,354
Accretion on collaboration, license and settlement agreements provision		308,938		693,047		5,129,758
Legal costs from financing activities		3,617,485		1,089,245		1,608,260
Other expenses		3,619,370		3,467,543		3,693,396
	$	14,081,153	$	10,013,732	$	16,438,936
Product development and clinical trials expenses
Depreciation		487,152		459,419		323,920
Share-based payments		1,764,557		1,252,218		974,629
Cash-based employee expenses		7,965,627		7,623,347		6,691,371
Other expenses		10,184,259		10,685,975		8,011,544
		20,401,595		20,020,959		16,001,464
TOTAL EXPENSES	$	36,679,551	$	31,680,676	$	33,793,565
Depreciation per Statements of Cash Flows	$	768,101	$	641,621	$	384,126
Share-based payments per Statements of Cash Flows	$	4,905,812	$	3,189,808	$	3,292,877
Cash-based employee expenses (see Note 20)	$	12,006,724	$	10,875,930	$	9,542,213