ACCOUNTS PAYABLE AND ACCRUED LIABILITIES

12 Months Ended

Dec. 31, 2018

ACCOUNTS PAYABLE AND ACCRUED LIABILITIES

ACCOUNTS PAYABLE AND ACCRUED LIABILITIES

13.    ACCOUNTS PAYABLE AND ACCRUED LIABILITIES

	December 31,		December 31,		December 31,
	2018		2017		2016
Trade payables	$	898,711	$	1,256,795	$	943,922
Accrued liabilities		5,247,431		346,984		217,036
Accrued vacation		142,730		157,198		1,270,306
Accrued employee termination expenses		373,171		—		—
Other accounts payable		190,496		83,978		59,679
	$	6,852,539	$	1,844,955	$	2,490,943

Included in accounts payable and accrued liabilities are $1,379,790 related to settlement charges as part of a collaboration agreement and.$2,749,968 related to a settlement provision (Note 24).