X0306 4 2020-03-12 0 0001399529 Dicerna Pharmaceuticals Inc DRNA 0001480111 Doberstein Stephen K C/O DICERNA PHARMACEUTICALS, INC. 33 HAYDEN AVENUE LEXINGTON MA 02421 1 0 0 0 Director Stock Option (Right to Buy) 15.61 2020-03-12 4 A 0 25000 0.00 A 2030-03-11 Common Stock 25000 25000 D This option vests as to one-third of the underlying shares on the one year anniversary of the vesting start date of February 4, 2020 and as to the remaining two-thirds of the shares in eight quarterly installments thereafter, subject in each case to the Reporting Person's continued service on the board of directors of the Issuer through each applicable vesting date. /s/ John B. Green, attorney-in-fact 2020-03-16