X0306 4 2019-12-17 0 0001399529 Dicerna Pharmaceuticals Inc DRNA 0001259856 FAMBROUGH DOUGLAS C/O DICERNA PHARMACEUTICALS, INC. 33 HAYDEN AVENUE LEXINGTON MA 02421 1 1 0 0 Chief Executive Officer Common Stock 2019-12-17 4 S 0 56716 26.1344 D 14605 D Common Stock 2019-12-17 4 S 0 2305 26.9443 D 12300 D Common Stock 2019-12-18 4 M 0 80000 3.42 A 92300 D Common Stock 2019-12-18 4 S 0 78569 25.8479 D 13731 D Common Stock 2019-12-18 4 S 0 1431 27.0735 D 12300 D Employee Stock Option (Right to Buy) 3.42 2019-12-18 4 M 0 80000 0.00 D 2023-09-24 Common Stock 80000 201250 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $25.82 to $26.79, inclusive. The reporting person undertakes to provide to Dicerna Pharmaceuticals, Inc., any security holder of to Dicerna Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $26.82 to $27.08, inclusive. The reporting person undertakes to provide to Dicerna Pharmaceuticals, Inc., any security holder of Dicerna Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form 4. Includes shares acquired under the DRNA 2014 Employee Stock Purchase Plan in transactions that were exempt under Rule 16b-3(c). The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $25.60 to $26.5950, inclusive. The reporting person undertakes to provide to Dicerna Pharmaceuticals, Inc., any security holder of Dicerna Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $26.87 to $27.1950, inclusive. The reporting person undertakes to provide to Dicerna Pharmaceuticals, Inc., any security holder of Dicerna Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (5) to this Form 4. Vested 1/48 monthly on last day of each month with a vesting start date of 07/30/2013. /s/ John B. Green, attorney-in-fact 2019-12-19