X0306 5 2018-12-31 0 0 0 0001399529 Dicerna Pharmaceuticals Inc DRNA 0001259856 FAMBROUGH DOUGLAS C/O DICERNA PHARMACEUTICALS, INC. 87 CAMBRIDGEPARK DRIVE CAMBRIDGE MA 02140 1 1 0 0 Chief Executive Officer Employee Stock Option (right to buy) 16.30 2018-08-31 5 G 0 200000 0.00 D 2024-04-16 Common Stock 200000 271900 D Employee Stock Option (right to buy) 16.30 2018-08-31 5 G 0 200000 0.00 D 2024-04-16 Common Stock 200000 71900 D Employee Stock Option (right to buy) 16.30 2018-08-31 5 G 0 200000 0.00 A 2024-04-16 Common Stock 200000 200000 I By Trust Employee Stock Option (right to buy) 16.30 2018-08-31 5 G 0 200000 0.00 A 2024-04-16 Common Stock 200000 200000 I By Trust This transaction was a bona fide gift of vested stock options to an irrevocable trust for the reporting person's minor child (Child A Trust) for which the reporting person's spouse serves as trustee. The reporting person disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. This transaction was a bona fide gift of vested stock options to an irrevocable trust for the reporting person's minor child (Child B Trust) for which the reporting person's spouse serves as trustee. The reporting person disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. This option vested in 48 monthly installments over the four-year period commencing January 30, 2014, and was fully vested and exercisable on January 30, 2018. /s/ John B. Green, attorney-in-fact 2019-02-08