X0306 4 2018-06-21 0 0001399529 Dicerna Pharmaceuticals Inc DRNA 0001230836 MADDEN DAVID C/O DICERNA PHARMACEUTICALS, INC. 87 CAMBRIDGEPARK DRIVE CAMBRIDGE MA 02140 1 0 0 0 Director Stock Option (right to buy) 13.08 2018-06-21 4 A 0 33000 0.00 A 2028-06-21 Common Stock 33000 33000 D This option vests monthly over 12 months from June 21, 2018 ("Grant Date") in substantially equal monthly installments, provided that the option will vest in full on the Issuer's next regularly scheduled annual meeting of stockholders that occurs following the Grant Date, subject to the Reporting Person's continued service to the Issuer through each such date or, if earlier, such annual meeting. /s/ John B. Green, attorney-in-fact 2018-06-25