X0306 4 2016-11-16 0 0001399529 Dicerna Pharmaceuticals Inc DRNA 0001274225 LANGER DENNIS C/O DICERNA PHARMACEUTICALS, INC. 87 CAMBRIDGEPARK DRIVE CAMBRIDGE MA 02140 1 0 0 0 Common Stock 2016-11-16 4 S 0 23766 3.52 D 71428 I Langer Family Holdings, LLLP Common Stock 43595 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.50 to $3.63, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4. The reporting person disclaims beneficial ownership of the shares owned by Langer Family Holdings, LLLP. Exhibit 24.1 - Power of Attorney /s/ John B. Green, attorney-in-fact 2016-11-17