X0101 EFFECT 33 LIVE 2009-11-30 0000950123-09-066725 485APOS 0001398956 Morgan Stanley Series Funds 333-143505 S000021245 Morgan Stanley Commodities Alpha Fund C000060577 Class A S000021245 Morgan Stanley Commodities Alpha Fund C000060578 Class C S000021245 Morgan Stanley Commodities Alpha Fund C000060579 Class I S000021245 Morgan Stanley Commodities Alpha Fund C000060580 Class R S000021245 Morgan Stanley Commodities Alpha Fund C000064959 Class W S000021245 Morgan Stanley Commodities Alpha Fund C000082411 CLASS B