Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Statement [Abstract]
Revenues	$ 47,680	$ 50,832
Costs and expenses:
Manufacture and supply	19,386	14,989
Research and development	17,481	17,047
Selling, general and administrative	52,879	53,475
Total costs and expenses	89,746	85,511
Loss from operations	(42,066)	(34,679)
Other income (expenses):
Interest expense	(6,552)	(10,049)
Interest expense related to the sale of future revenue	(5,891)	(12,412)
Interest income and other income, net	99	423
Loss on the extinguishment of debt	0	(13,822)
Net loss before income taxes	(54,410)	(70,539)
Income taxes	0	0
Net loss	(54,410)	(70,539)
Comprehensive loss	$ (54,410)	$ (70,539)
Net loss per share - basic (in usd per share)	$ (1.12)	$ (1.85)
Net loss per share - diluted (in usd per share)	$ (1.12)	$ (1.85)
Weighted-average number of common shares outstanding - basic (in shares)	48,734,377	38,077,660
Weighted-average number of common shares outstanding - diluted (in shares)	48,734,377	38,077,660