Sale of Future Revenue - Royalty Obligation (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Sale of Future Revenue [Roll Forward]
Liability related to the sale of future revenue, net at December 31, 2021			$ 60,284
Royalties related to the sale of future revenue	$ 13,265	$ 15,345	25,535	$ 26,467
Amortization of issuance costs			101
Interest expense related to the sale of future revenue			3,722	$ 6,729
Liability related to the sale of future revenue, net (includes current portion of $1,445)	63,284		63,284
Current portion	$ 1,445		1,445
Royalty
Sale of Future Revenue [Roll Forward]
Royalties related to the sale of future revenue			$ (823)