Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Income Statement [Abstract]
Revenues	$ 13,265,000	$ 15,345,000	$ 25,535,000	$ 26,467,000
Costs and expenses:
Manufacture and supply	5,242,000	4,466,000	9,456,000	7,223,000
Research and development	5,198,000	4,262,000	9,971,000	7,921,000
Selling, general and administrative	15,587,000	13,134,000	28,608,000	26,365,000
Total costs and expenses	26,027,000	21,862,000	48,035,000	41,509,000
Loss from operations	(12,762,000)	(6,517,000)	(22,500,000)	(15,042,000)
Other income/ (expenses):
Interest expense	(1,635,000)	(2,757,000)	(3,253,000)	(5,518,000)
Interest expense related to the sale of future revenue, net	(1,937,000)	(3,466,000)	(3,798,000)	(6,800,000)
Interest and other income, net	32,000	373,000	29,000	321,000
Net loss before income taxes	(16,302,000)	(12,367,000)	(29,522,000)	(27,039,000)
Income taxes	0	0	0	0
Net loss	(16,302,000)	(12,367,000)	(29,522,000)	(27,039,000)
Comprehensive loss	$ (16,302,000)	$ (12,367,000)	$ (29,522,000)	$ (27,039,000)
Net loss per share - basic (in dollars per share)	$ (0.36)	$ (0.33)	$ (0.68)	$ (0.74)
Net loss per share - diluted (in dollars per share)	$ (0.36)	$ (0.33)	$ (0.68)	$ (0.74)
Weighted-average number of common shares outstanding - basic (in shares)	45,462,516	37,065,300	43,475,198	36,318,437
Weighted-average number of common shares outstanding - diluted (in shares)	45,462,516	37,065,300	43,475,198	36,318,437