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Share-Based Compensation (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Share-based Compensation expenses [Abstract]    
Share-based compensation expenses $ 913 $ 1,507
Employee Stock Purchase Plan    
Share-based Compensation expenses [Abstract]    
Share-based compensation expenses 0 0
Restricted stock units    
Share-based Compensation expenses [Abstract]    
Share-based compensation expenses $ 0 38
Number of Units    
Unvested, at beginning of period (in shares) 0  
Granted (in shares) 166  
Vested (in shares) 0  
Forfeited (in shares) 0  
Unvested, at end of period (in shares) 166  
Weighted Average Grant Date Fair Value    
Unvested, at beginning of period (in dollars per share) $ 0  
Granted (in dollars per share) 2.55  
Vested (in dollars per share) 0  
Forfeited (in dollars per share) 0  
Unvested, at end of period (in dollars per share) $ 0  
Grant date fair value of shares vested during the period $ 0  
Unrecognized compensation costs of RSU awards 377  
Compensation Cost Not yet Recognized [Abstract]    
Unrecognized compensation expense related to non-vested stock options $ 377  
Unrecognized compensation cost, recognition period 2 years 11 months 8 days  
Stock options    
Share-based Compensation expenses [Abstract]    
Share-based compensation expenses $ 913 1,469
Number of Options    
Outstanding at beginning of period (in shares) 4,146  
Granted (in shares) 1,125  
Exercised, Forfeited, Expired (in shares) (11)  
Outstanding at end of period (in shares) 5,260  
Vested or expected to vest at end of period (in shares) 5,047  
Exercisable at end of period (in shares) 2,496  
Weighted Average Exercise Price    
Outstanding at beginning of period (in dollars per share) $ 7.28  
Granted (in dollars per share) 2.55  
Exercised, Forfeited, Expired (in dollars per share) 4.98  
Outstanding at end of period (In dollars per share) 6.27  
Vested or expected to vest at end of period (in dollars per share) 6.39  
Exercisable at end of period (in dollars per share) $ 9.25  
Fair Value Assumptions [Abstract]    
Expected dividend yield 0.00%  
Expected volatility 100.00%  
Expected term (years) 6 years 1 month 6 days  
Risk-free interest rate 2.00%  
Weighted average grant date fair value (in dollars per share) $ 2.03  
Additional Disclosures [Abstract]    
Share price (in dollars per share) $ 2.61  
Compensation Cost Not yet Recognized [Abstract]    
Unrecognized compensation expense related to non-vested stock options $ 5,098  
Unrecognized compensation cost, recognition period 2 years 25 days  
Stock options | Minimum    
Additional Disclosures [Abstract]    
Share price (in dollars per share) $ 2.55  
Manufacture and supply    
Share-based Compensation expenses [Abstract]    
Share-based compensation expenses $ 48 82
Research and development    
Share-based Compensation expenses [Abstract]    
Share-based compensation expenses 169 232
Selling, general and administrative    
Share-based Compensation expenses [Abstract]    
Share-based compensation expenses $ 696 $ 1,193