Share-Based Compensation - Expense (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total share-based compensation expenses	$ 6,819	$ 6,581
Restricted Stock Units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total share-based compensation expenses	81	806
Stock Options
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total share-based compensation expenses	6,714	5,751
Employee Stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total share-based compensation expenses	24	24
Manufacture and supply
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total share-based compensation expenses	313	275
Research and development
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total share-based compensation expenses	881	729
Selling, general and administrative
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total share-based compensation expenses	$ 5,625	$ 5,577