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Material Agreements (Details) - USD ($)
$ in Thousands
1 Months Ended 2 Months Ended 3 Months Ended 6 Months Ended 8 Months Ended 17 Months Ended 63 Months Ended
Nov. 03, 2020
Nov. 30, 2020
Jun. 30, 2020
Dec. 31, 2020
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Feb. 20, 2019
Jun. 30, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues         $ 15,345 $ 21,675 $ 26,467 $ 30,440      
License and royalty revenue                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues         2,311 12,928 $ 4,672 $ 13,354      
Commercial Exploitation Agreement with Indivior                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
License agreement term             7 years        
Automatic renewal period of agreement             1 year        
Commercial Exploitation Agreement with Indivior | Minimum                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Notice period of intent not to renew agreement             1 year        
Supplemental Agreement with Indivior                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Contingent payments receivable in the future         34,250   $ 34,250   $ 34,250   $ 34,250
Revenues                   $ 40,750  
Supplemental Agreement with Indivior | Maximum                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Contingent payments receivable in the future         75,000   75,000   75,000   75,000
Supplemental Agreement with Indivior Performance or Event-Based Milestones                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Contingent payments receivable in the future         33,000   33,000   33,000   33,000
Supplemental Agreement with Indivior Additional Process Patent Rights to the Company                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Contingent payments receivable in the future         1,250   1,250   1,250   1,250
License Agreement with Sunovion Pharmaceuticals, Inc.                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues                     22,000
License Agreement with Sunovion Pharmaceuticals, Inc. | License and royalty revenue                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues           $ 8,000          
License Agreement with Sunovion Pharmaceuticals, Inc Milestones                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues                     17,000
License Agreement with Sunovion Pharmaceuticals, Inc Milestones | License and royalty revenue                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues             $ 4,000        
License Agreement with Sunovion Pharmaceuticals, Inc. Upfront                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues                     $ 5,000
Marathon Pangolin Royalty LLC | Monetization Agreement                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Proceeds from sale of future revenue $ 40,000     $ 10,000         $ 50,000    
Proceeds from debt, contingent on additional milestones   $ 75,000                  
Marathon Pangolin Royalty LLC | Maximum                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Proceeds from sale of future revenue $ 125,000                    
Agreement to Terminate CLA with KemPharm | License and royalty revenue                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Revenues     $ 500   $ 2,000