Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Condensed Consolidated Statements of Operations and Comprehensive Loss [Abstract]
Revenues	$ 11,122	$ 8,765
Costs and expenses:
Manufacture and supply	2,757	3,659
Research and development	3,659	4,354
Selling, general and administrative	13,231	14,613
Total costs and expenses	19,647	22,626
Loss from operations	(8,525)	(13,861)
Other income (expenses):
Interest expense	(2,761)	(2,771)
Interest expense related to the sale of future revenue, net	(3,334)	0
Interest income and other income (expense), net	(52)	102
Net loss before income taxes	(14,672)	(16,530)
Income taxes	0	0
Net loss	(14,672)	(16,530)
Comprehensive loss	$ (14,672)	$ (16,530)
Net loss per share - basic (in dollars per share)	$ (0.41)	$ (0.49)
Net loss per share - diluted (in dollars per share)	$ (0.41)	$ (0.49)
Weighted-average number of common shares outstanding - basic (in shares)	35,563,275	33,569,694
Weighted-average number of common shares outstanding - diluted (in shares)	35,563,275	33,569,694