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Income Taxes (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Deferred tax assets [Abstract]    
Accounts receivable $ 112 $ 126
Inventory 4 69
Accrued expenses 353 835
NOL carryforwards 22,569 23,687
Interest limitation imposed by the TJCA 7,235 5,748
Stock Compensation 4,051 2,505
Other 1,229 783
Sale of Future Revenue 14,444 0
Property and equipment 2,380 1,741
Orphan Drug and R&D Tax Credits 5,851 4,621
Deferred tax assets 58,228 40,115
Deferred tax liabilities [Abstract]    
Intangible assets (551) (58)
Prepaid expenses (908) 0
Deferred tax liabilities (1,459) (58)
Valuation Allowance (56,769) (40,057)
Net deferred tax asset/(liability) 0 0
Unrecognized Tax Benefits [Abstract]    
Unrecognized tax benefits 0 0
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued [Abstract]    
Penalties and interest accrued $ 0 $ 0
Reconciliation of Income Tax Benefit [Abstract]    
Income taxes at statutory rate 21.00% 21.00%
Increase (decrease) resulting from [Abstract]    
State income tax 6.81% 6.76%
Permanent differences (0.12%) (0.04%)
Research & development credit 2.35% 2.32%
Return to provision 0.00% 0.98%
Valuation allowance (30.04%) (31.02%)
Effective tax rate 0.00% 0.00%
Federal [Member]    
Deferred tax liabilities [Abstract]    
Operating loss carryforwards $ 81,566 $ 85,905
State [Member]    
Deferred tax liabilities [Abstract]    
Operating loss carryforwards $ 74,379 $ 80,266